Biomedical Product Design

Description

Research activities fall within the field of human modeling. These are divided into the following macro-areas:

  • Study of obstructive sleep apnea syndrome
    • Development of numerical models to simulate the behavior of the effects of mandibular advancement devices on patients.
    • Development of a patent-pending device for measuring the force and displacement of mandibular protrusion and retrusion, and characterization of the temporomandibular joint.
  • Design of customized prosthetics
    • Development of customized implantable prosthetics used in maxillofacial surgery for the restoration of fractured orbital floors or walls, or in cosmetic surgery for patients with rare syndromes.
    • Development of devices to support the surgeon in the placement of customized prosthetics, ensuring correct positioning and orientation.
  • Extended Reality solutions for maxillofacial surgery
    • Development of an eXtended Reality application for virtual surgery. An application capable of guiding the surgeon during osteotomies and the repositioning of bone fragments in facial surgery.
Publications
  • Brunzini, A., Mazzoli, A., Pagnoni, M., Mandolini, M., 2023. An innovative mixed reality approach for maxillofacial osteotomies and repositioning. Virtual Real. https://doi.org/10.1007/s10055-023-00867-z
  • Caragiuli, M., Candelari, M., Zalunardo, F., Bruno, G., de Stefani, A., Brunzini, A., Mandolini, M., 2024. Effects of Oral Appliances for Obstructive Sleep Apnoea in Reduced Periodontium: A Finite Element Analysis. Int Dent J 74, 1306–1316. https://doi.org/10.1016/j.identj.2024.05.002
  • Caragiuli, M., Mandolini, M., Landi, D., Bruno, G., de Stefani, A., Gracco, A., Toniolo, I., 2021. A finite element analysis for evaluating mandibular advancement devices. J Biomech 119, 110298. https://doi.org/10.1016/j.jbiomech.2021.110298
  • Mandolini, M., Brunzini, A., Caragiuli, M., Mazzoli, A., Pagnoni, M., 2022a. An innovative orbital implant positioner for the proper restoration of eye-socket defects. Biodes Manuf. https://doi.org/10.1007/s42242-022-00217-z
  • Mandolini, M., Brunzini, A., Facco, G., Mazzoli, A., Forcellese, A., Gigante, A., 2022b. Comparison of Three 3D Segmentation Software Tools for Hip Surgical Planning. Sensors 22, 5242. https://doi.org/10.3390/s22145242
Staff

Prof. Marco Mandolini 
Tel. +39 071 220 4799
E-mail: m.mandolini@staff.univpm.it