Biomedical product design


The research activity in the biomedical field refers to the study and development of software tools for the design of medical devices, as well as the use of commercial tools for the characterization of medical devices and human joints.
Here are some projects.
Design of CAD tools for the design of orthopedic diabetic shoes
Software tool for 3D design of custom shapes

Software tool for 3D design of custom orthotics

Design of customized prostheses and surgical guides for reconstruction of fractured orbits or for the correction of congenital malformations

Study of the effects due to mandibular advancement devices at the temporomandibular joint level and periodontal ligaments, within the Obstructive Sleep Apnea Syndrome


Activities are carried out in the Virtual Prototyping laboratory.

  1. Davia, M., Germani, M., Mengoni, M., Montiel, E., & Raffaeli, R. (2011). Shoes Customization Design Tools for the “Diabetic Foot.” Computer-Aided Design and Applications, 8(5), 693–711.
  2. Bernabéu, J. A., Germani, M., Mandolini, M., Mengoni, M., Nester, C., Preece, S., & Raffaeli, R. (2013). CAD tools for designing shoe lasts for people with diabetes. Computer-Aided Design, 45(6), 977–990.
  3. Mandolini, M., Carloni Vitali, M., Macchione, A., Raffaeli, R., & Germani, M. (2015). A CAD Tool to Design Bespoke Insoles for Severe Orthopaedic Treatments. Computer-Aided Design and Applications, (May 2015), 700–709.
  4. Mandolini, M., Brunzini, A., Steve, M., & Germani, M. (2017). Foot plantar pressure offloading: how to select the right material for a custom made insole. In Proceedings of the 21st International Conference on Engineering Design (ICED17 (Vol. 1: Resourc, pp. 469–478). Vancouver, Canada.
  5. Carloni Vitali, M., Germani, M., Mandolini, M., & Raffaeli, R. (2014). A new business model for the orthopaedic and customized cust omized footwear sector. In D. Marjanović, M. Štorga, N. Pavković, & N. Bojčetić (Eds.), Proceedings of the DESIGN 2014 13th International Design Conference (pp. 771–782). Dubrovnik. Retrieved from
  6. Mandolini, M., Brunzini, A., & Germani, M. (2017). A collaborative web-based platform for the prescription of Custom-Made Insoles. Advanced Engineering Informatics, 33, 360–373.
  7. Brunzini, A., Gracco, A., Mazzoli, A., Mandolini, M., Manieri, S., & Germani, M. (2018). Preliminary simulation model toward the study of the effects caused by different mandibular advancement devices in OSAS treatment. Computer Methods in Biomechanics and Biomedical Engineering, 0(0), 1–10.
  8. Mandolini, M., Brunzini, A., Germani, M., Manieri, S., Mazzoli, A., & Pagnoni, M. (2019). Selective laser sintered mould for orbital cavity reconstruction. Rapid Prototyping Journal, 25(1), 95–103.
  9. Stefani, A. De. (2018). Strength distribution on TMJ using mandibular advancement device for OSAS treatment : a finite element study, 86(9), 757–764.
  10. Brunzini, A., Mandolini, M., Manieri, S., Germani, M., Mazzoli, A., Pagnoni, M., … Modugno, A. (2017). Orbital Wall Reconstruction by Selective Laser Sintered Mould. In Biomedical Engineering (Vol. 5, pp. 260–264). Calgary,AB,Canada: ACTAPRESS.
Scientific Manager
Working group